EMERGING PHAACEUTICAL APPLICATIONS OF PIPERIDINE, PYRROLIDINE AND IT S DERIVATIES
Shazia Haider, Zafar Saeed Saify*, Nasreen Begum, Seema Ashraf, Tabinda Zarreen, S.M.Ghufran Saeed
Journal Title:World Journal of Pharmaceutical Research
Heterocyclic compounds form largest classical division of organic chemistry by gaining enormous importance in industry and biology. .
The mainstream of pharmaceuticals is heterocyclic. Numerous
modifiers and stabilizers used in different industrial applications such as cosmetics, information storage, plastics, optics, electronics and reprography along with biologically active agrochemicals are
heterocyclic in nature. Pyrrolidine and piperidine both secondary amines are members of saturated heterocyclic compounds demands main cause of interest for chemists, biologist and pharmacist due to their significant and diverse range of promising biological activities
like analgesic, anti-inflammatory, CNS, antioxidant, antihistaminic, cytotoxic, antimicrobial
and others from last few decades. In the present review we attempts to give information about the synthesis and biological activities of various kinds of Pyrrolidine and piperidine
derivatives which might be helpful for both pharmaceutical and chemist in further research.