OXIDATIVE STRESS STATUS IN OBESITY ALGERIANS POPULATION
Karouche Saida*, Rouabah Leila
, Ameddah Souad, Benlatreche Moufida, Bellil Ines, Hamma Sihem Amina, Rouabah Abdelkader
Journal Title:World Journal of Pharmaceutical Research
Methods: To realise this study, a survey of anthropometric measurement was carried out on 61 subjects with a BMI ? 25, aged 20
to 67 years, were recruited at the city of Ain Fakroun, and located in
eastern Algeria. Blood assays include at fasting blot biochemical assays, vitamin E, A, and antioxidant status. Results: Antioxidant serum levels of vitamins E/A, GSH and catalase activity is higher
among overweight subject than in obese subject (BMI ? 30) with increase in the MDA levels (P < 0.05). Catalase activity is
significantly (P < 0.05) lower in the obesity group; however the SOD activity was not decreased. Plasma levels of total cholesterol, triglycerides and fasting glucose were significantly higher in obese subjects (P < 0.05). A reduced antioxidant status in women serum is associated with an increase in the percentage of physical inactivity (P < 0.05). According to these results, women are in the early stages of obesity against the latter persists long in men.
Blood pressure was positively associated with waist circumference, obesity and age, obesity increases with age (P < 0.05). Conclusion: These preliminary results reveal that obesity reduces the serum levels of antioxidant status.