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Paper Details

SYNTHESIS, CHARACTERIZATION AND ANTI-MICROBIAL ACTIVITY OF SUBSTITUTED BENZOXAZOLE DERIVATIVES

*D.Maruthamuthu, Shameela Rajam, Christina Ruby Stella, Ranjith, Rajakumar

Journal Title:World Journal of Pharmaceutical Research
Abstract


A Series of some novel benzoxazole compounds were synthesized and evaluated for anti-microbial activity. The reaction of o-aminophenol with dicarboxylic acid yield substituted benzoxazole. The title compounds were synthesized by treating substituted benzoxazole with oxalic acid,cinnamicacid, succinic acid,phthalic acid,salicylic acid.Their structures were confirmed by IR, 1 HNMR, and 13 CNMR. Anti-microbial activity against staphylococclus aureus was studied for the synthesized compounds.

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