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Paper Details


Sivaleela C*, Pragathi E

Journal Title:World Journal of Pharmaceutical Research

Introduction- Urinary tract infection (UTI) is the second most common infectious presentation in community practice. The most common pathogenic organisms of UTI are Escherichia coli, Staphylococcus saprophyticus . Treatmentof UTI cases is often started empirically and therapy is based on information determined from the antimicrobial resistance pattern of the urinary pathogens.The aim of the study was to determine the prevalence of organisms that causes urinary tract infections and the antibiotic sensitivity and resistance pattern of pathogenic organisms isolated. Materials and Methods- A total of 100 urine samples were screened for pathogenic organisms. 5-10 ml of single clean catch midstream urine was collected from symptomatic patients of urinary tract infection.The samples were inoculated on Blood agar, MacConkey agar, Cystine Lactose Electrolyte Deficient agar (CLED), Urichrome (Himedia) agar. Culture plates were incubated aerobically at 37?C for 18-24 hours.The isolated organism was identified by standard biochemical tests and antibiogram was done. Results Out of 100 samples, females were of 76% and males 34%. Urinary tract infections were most commonly found in the age group between 31 -40 years in females and 36-40 years in males.The most common isolate was Escerichia coli(58.3%). Conclusion - A high prevalence of ESBL(Extended Spectrum Beta Lactamases) and AmpC beta lactamase in community acquired infection is a matter of concern. It is quite alarming to note that, multidrug resistant isolates including ESBL and AmpC beta lactamase producing bacteria circulating in community. Henceforth it is important to formulate a strict antibiotic policy.