MONTMORILLONITE: A MILD AND EFFICIENT RECYCLABLE SOLID ACID CATALYST FOR DETRITYLATION OF TRITYL TETRAZOLE IN SARTAN MOLECULES
D. Raju, G. Prabhakar, *B. Madhavarao, K. Sudhakar, M. Rajesh, B. M. Choudary
Journal Title:World Journal of Pharmaceutical Research
Proton and metal ion-exchanged Montmorillonite catalyzes the
detritylation of trityl tetrazole in sartan molecules under mild
conditions in high yields. The reactions are carried out in methanol in
presence of 1 equivalents of water. Catalyst was reusable without any
appreciable loss in its catalytic activity .