ANALGESIC AND ANTIEMETIC ACTIVITIES OF FICUS EXASPERATA VAHL., AND CLEOME CILIATA SCHMACH AND THONN.
Misbah Zubair, Syed Waseemuddin Ahmed, Salman Ahmed*, M.Shaiq Ali and Patrricia Akpomedaye Onocha
Journal Title:World Journal of Pharmaceutical Research
The present investigation is an attempt to evaluate analgesic and
antiemetic activities of Ficus exasperata; Cleome ciliata leaves
methanolic extract by using chick emesis model (oral treatment) and
acetic acid induced writhing test (intraperitoneal treatment) in mice
respectively. The antiemetic activity (150 mg/kg b.w., of extract) was
carried out by using chlorpromazine (150mg/kg) as standard antiemetic
drug. The analgesic activity (250 mg/kg b.w., of extract) was
performed by using aspirin (150mg/kg) as standard analgesic drug. The
results showed significant analgesic and antiemetic effects.