• We are available for your help 24/7
  • Email: info@isindexing.com, submission@isindexing.com


Paper Details

ANTICANCER ACTIVITY OF JELLYFISH, CHRYSAORA QUINQUECIRRHA (DESOR 1848) FROM VELLAR ESTUARY, SOUTHEAST COAST OF INDIA

Suganthi Krishnan*, Perumal Pachiappan, Tufail Ahmed Mazharbasha and Keerthana Ranganathan

Journal Title:World Journal of Pharmaceutical Research
Abstract


Background: Marine organisms are considered to be an inexhaustible source of chemical compounds that produce a wide variety of biologically active secondary metabolites. Scyphozoan jellyfishes have become an important target for the biotechnology industry because of the large number of bioactive compounds recently discovered from them. Objective: The present investigation pertains to the evaluation of the anticancer activity of extracts of jellyfish Chrysaora quinquecirrha, collected from Vellar estuary, South east coast of India. Methodology: The nematocyst extracts of tentacles of jellyfish were characterized for protein contents and their anticancer potential was determined on human lung cancer cell lines (A549) with 205.0 g GI50 . Results: The study showed that the extracted peptides could be amino acid residues (secondary amides) which might be responsible for the anticancer potential on human lung cancer cell lines (A549). Conclusions: Marine organisms are considered to be an inexhaustible source of chemical compounds that produce a wide variety of biologically active secondary metabolites. Scyphozoan jellyfishes have become an important target for the biotechnology industry because of the large number of bioactive compounds recently discovered from them. This paper focuses on the anticancer potential of marine species with certain pharmaceutical interest, which could confer anticancer activity.

Download