COMMUNITY ASSOCIATED METHICILLIN RESISTANT S.aureus (CA-MRSA) INFECTIONS
Javid Ahmad Bhat*, Rajesh Kumar Tenguria
Journal Title:World Journal of Pharmaceutical Research
Staphylococcus aureus is a bacterium commonly found on the skin,
axillae, perineum, and in the nares of healthy individuals. At least 30%
of the population may permanently or intermittently carry S. aureus.
Staphylococcus aureus is one of the most common and important
pathogen, responsible for the majority of nosocomial infections.
S.aureus is an opportunistic bacterium, normally, part of the human
micro-flora but, attacks immediately when the immune system of the
host becomes susceptible. MRSA associated with healthcare has posed
a major problem throughout the world. The recent rapid rise of
community-associated MRSA (CA-MRSA) has further added to the
burden of MRSA infections. Thus, attention has been increasingly focused on the severity
and frequency of infections caused by MRSA, and its greater clinical and economic impact
compared to methicillin-susceptible S. aureus (MSSA). Infections caused by communityacquired methicillin resistant Staphylococcus aureus (CA-MRSA) have become epidemic
over the last decade. Treatment of infections caused by this organism is problematic due to its
resistance to many drugs. Recent reports of community-associated MRSA (CA-MRSA)
infections in patients with no known risk factors have serious public health implications.
Therapeutic options for these infections are untested; therefore, the potential exists for high
morbidity and mortality.