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Paper Details

EFFECTIVENESS OF TINOSPORA CORDIFOLIA ON STAPHYLOCOCCUS, STREPTOCOCCUS, KLEBSIELLA AND CANDIDA SPECIES AMONG HIV INFECTED CHILDREN - A RANDOMISED CONTROL TRIAL.

Dr. Tom Peter*, Dr. Vijaya Hegde, Dr. Rajani Mary George and Dr. Eby Aluckal

Journal Title:World Journal of Pharmaceutical Research
Abstract


Acquired Immuno Deficiency Syndrome (AIDS) is one of the major global health concerns. Lack of immunity and opportunistic infections are the major threat to these patients. Ayurveda has been of immense help in managing these type of patients. The present study was conducted to assess the anti bacterial and anti fungal effectiveness of Tinospora cordifolia and to compare its effect with chlorhexidene. Saliva and swab specimens were collected from 12 people living with HIV infection. Study subjects were divided into two groups and one group was given chlorhexidene and other group Tinospora cordifolia leaves. Saliva and swab samples were taken before and after, and sent for microbial analysis. Statistical analysis of the results revealed that there is no statistical significance between the two groups. ( p > 0.05). From the present study, we can conclude that both Tinospora cordifolia and chlorhexidene have antibacterial and antifungal effectiveness and since Tinospora cordifolia is locally available, it can be used as an adjuvant to oral hygiene practice, especially in case of AIDS patients who are more prone to opportunistic infections.

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