HYSTEROSCOPY FINDINGS IN WOMEN WITH IMPLANTATION FAILURE AFTER IN VITRO FERTILIZATION (IVF)
Roshan Nikbakht, Kobra Shojaei*, Neda Torabifar
Journal Title:World Journal of Pharmaceutical Research
Objectives: The aim of this study was to assess the uterine cavity by
hysteroscopy of women with infertility and implantation failure.
Intrauterine environment plays a major role in implantation and
achievement in clinical pregnancy. Materials & Methods: This
research was a cross sectional study which included 80 patients with
primary or secondary infertility with also one or more In Vitro
Fertilitisation (IVF) cycles failed despite of good quality of embryo
transfer and normal appearance of the uterine cavity in
hysterosalpingography. All patients were examined by transvaginal
ultrasonography (TVU) and then hysteroscopy. Evaluation of the
uterine cavity, endometrium and tubal Ostia were performed by
hysteroscopy and findings were recorded. Patients with severe cervical
stenosis were excluded from the study. A patient with noted uterine
cavity pathology appropriate surgical management was administered in same setting.
Results: A total of 46.2% of the study population showed abnormality in hysteroscopy of
uterine cavity. Abnormal hysteroscopic findings were including: uterine sub septum (25%),
endometrial polyps (13/8%), endometrial adhesion (6.2%), and submucousal myoma (1.2%).
Conclusions: Reevaluating the uterine cavity by hysteroscopy prior to further IVF embryo
transfer cycles can be suggested to women with implantation failure to determine intrauterine
cavity abnormality and treatment of them to enhance the clinical pregnancy.