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Paper Details

HYSTEROSCOPY FINDINGS IN WOMEN WITH IMPLANTATION FAILURE AFTER IN VITRO FERTILIZATION (IVF)

Roshan Nikbakht, Kobra Shojaei*, Neda Torabifar

Journal Title:World Journal of Pharmaceutical Research
Abstract


Objectives: The aim of this study was to assess the uterine cavity by hysteroscopy of women with infertility and implantation failure. Intrauterine environment plays a major role in implantation and achievement in clinical pregnancy. Materials & Methods: This research was a cross sectional study which included 80 patients with primary or secondary infertility with also one or more In Vitro Fertilitisation (IVF) cycles failed despite of good quality of embryo transfer and normal appearance of the uterine cavity in hysterosalpingography. All patients were examined by transvaginal ultrasonography (TVU) and then hysteroscopy. Evaluation of the uterine cavity, endometrium and tubal Ostia were performed by hysteroscopy and findings were recorded. Patients with severe cervical stenosis were excluded from the study. A patient with noted uterine cavity pathology appropriate surgical management was administered in same setting. Results: A total of 46.2% of the study population showed abnormality in hysteroscopy of uterine cavity. Abnormal hysteroscopic findings were including: uterine sub septum (25%), endometrial polyps (13/8%), endometrial adhesion (6.2%), and submucousal myoma (1.2%). Conclusions: Reevaluating the uterine cavity by hysteroscopy prior to further IVF embryo transfer cycles can be suggested to women with implantation failure to determine intrauterine cavity abnormality and treatment of them to enhance the clinical pregnancy.

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